Choroidal Neovascularization in Primary Membranous Nephropathy
Autor: | Lorena Francescutti, Tommaso Gambato, Paolo Lanzetta |
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Rok vydání: | 2020 |
Předmět: |
Male
medicine.medical_specialty genetic structures Angiogenesis Inhibitors 030204 cardiovascular system & hematology Membranous Glomerulonephritis Membranous Serous Retinal Detachment Central Serous Chorioretinopathy Choroidal Neovascularization 03 medical and health sciences chemistry.chemical_compound Glomerulonephritis 0302 clinical medicine Membranous nephropathy Ophthalmology Humans Medicine Metamorphopsia Fluorescein Angiography business.industry Retinal Detachment Retinal Articles General Medicine Middle Aged medicine.disease Dilated fundus examination eye diseases Bevacizumab Serous fluid Choroidal neovascularization chemistry 030220 oncology & carcinogenesis Intravitreal Injections sense organs medicine.symptom business Tomography Optical Coherence |
Zdroj: | The American Journal of Case Reports |
ISSN: | 1941-5923 |
DOI: | 10.12659/ajcr.923454 |
Popis: | Patient: Male, 61-year-old Final Diagnosis: Choroidal neovascularization Symptoms: Decrease in the visual acuity • metamorphopsia Medication:— Clinical Procedure: — Specialty: Nephrology • Ophthalmology Objective: Rare co-existance of disease or pathology Background: We describe the retinal findings in a patient affected by primary membranous nephropathy (MN). Case Report: A 61-year-old man presented with a 3-month history of metamorphopsia and decreased visual acuity in both eyes. He was affected by nephrotic syndrome in primary MN and treated with systemic corticosteroids. Dilated fundus examination, optical coherence tomography, and fundus fluorescein angiography revealed the presence of peripapillary choroidal neovascularization (CNV) in the right eye and peripheral CNV in the left eye. A serous retinal detachment with gravitational tract was also observed in both eyes. The patient was treated with intravitreal bevacizumab in the right eye and oral corticosteroids were discontinued. Both eyes achieved a morphological and functional improvement. Conclusions: We present the first case of primary MN associated with CNV, possibly secondary to central serous chorioretinopathy, successfully treated with intravitreal bevacizumab and discontinuation of oral corticosteroids. |
Databáze: | OpenAIRE |
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