Screening for thyroid disease of 15-17-year-old schoolchildren in an area with normal iodine intake
| Autor: | Robert Eggertsen, Mille Milakovic, Göran Lindstedt, Gertrud Berg, E Nyström |
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| Rok vydání: | 2001 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Pediatrics endocrine system diseases Adolescent medicine.medical_treatment Thyroid Function Tests Thyroid function tests Thyroiditis Internal medicine Internal Medicine medicine Humans Mass Screening Euthyroid Mass screening Subclinical infection Aged Sweden medicine.diagnostic_test business.industry Antithyroid agent Thyroid disease Incidence Thyroid Thyroiditis Autoimmune Middle Aged medicine.disease Thyroid Diseases medicine.anatomical_structure Endocrinology Cross-Sectional Studies Female business |
| Zdroj: | Journal of internal medicine. 250(3) |
| ISSN: | 0954-6820 |
| Popis: | Milakovic M, Berg G, Eggersten R, Lindstedt G, Nystrom E (Sahlgrenska University Hospital, Goteborg, Sweden). Screening for thyroid disease of 15–17-year-old schoolchildren in an area with normal iodine intake. J Intern Med 2001; 250: 208–212. Objective. The prevalence of thyroid disease in Swedish schoolchildren is today insufficiently known. The aim of the study was therefore to determine the prevalence of abnormal thyroid function and thyroid autoimmunity in teen-age schoolchildren and to compare the findings with a healthy control group of 60–65-year-old inhabitants from the same community. Setting. A semirural community of approximately 15 000 inhabitants. Design. Cross-sectional study. Main outcome measures. Thyroid volume and serum concentrations of serum thyrotropin (TSH), total and free thyroxine (T4), total and free 3,5,3′-triiodothyronine (T3), and antithyroperoxidase antibodies (TPOAb). Results. Four schoolchildren (7%, 59 screened) had elevated TPOAb concentration, three of the subjects being girls (8%). One girl with a goitre was overtly hypothyroid and one girl showed borderline-high serum TSH concentration suggesting subclinical autoimmune thyroid disease. One euthyroid boy had a goitre and high concentration of TPOAb. The serum free T3 concentration was significantly higher in 15–17-year-old than 60–65-year-old (7.4 vs. 6.4 pmol L–1, P |
| Databáze: | OpenAIRE |
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