Strain and sex differences in amphetamine-induced rotation
| Autor: | H.J. Storrie-Baker, Douglas P. Crowne, M.F. Novotny |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Rotation Clinical Biochemistry Toxicology Biochemistry Rats sprague dawley Developmental psychology Rats Sprague-Dawley Behavioral Neuroscience Estrus Species Specificity Internal medicine medicine Animals Amphetamine Biological Psychiatry Pharmacology Sex Characteristics Strain (chemistry) Rats Directional bias Endocrinology Laterality Female Stereotyped Behavior Psychology medicine.drug Sex characteristics |
| Zdroj: | Pharmacology Biochemistry and Behavior. 43:795-797 |
| ISSN: | 0091-3057 |
| DOI: | 10.1016/0091-3057(92)90410-h |
| Popis: | Studies of rotational behavior in female rats have investigated Fischer, Sprague-Dawley, Madison, WI, and Holtzman strains. The present study of amphetamine-induced rotational preference looked at the most widely used of the pigmented strains, Long-Evans hooded rats, examining rotation in females and comparing rotational magnitude and direction to males of the same strain. We corroborate in Long-Evans animals the greater rotation of females, but our findings oppose the right-sided female and left-sided male rotational preferences reported in earlier studies. Only female rats in this experiment had a significant directional bias, and it was to the left. This result strongly points to the importance of strain in the lateralization expressed by rotation. |
| Databáze: | OpenAIRE |
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