Comparative minicolumnar morphometry of three distinguished scientists
| Autor: | Manuel F. Casanova, Michael Fitzgerald, Juan Trippe, Andrew E. Switala |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Aged 80 and over Male Neurons Intelligence Cell Culture Techniques Diagnostic test Brain Cognition 030229 sport sciences Middle Aged medicine.disease Developmental psychology 03 medical and health sciences 0302 clinical medicine Interpersonal competence Developmental and Educational Psychology medicine Autism Educational Status Humans Communication skills Psychology Dominance Cerebral 030217 neurology & neurosurgery |
| Zdroj: | Autism : the international journal of research and practice. 11(6) |
| ISSN: | 1362-3613 |
| Popis: | It has been suggested that the cell minicolumn is the smallest module capable of information processing within the brain. In this case series, photomicrographs of six regions of interests (Brodmann areas 4, 9, 17, 21, 22, and 40) were analyzed by computerized image analysis for minicolumnar morphometry in the brains of three distinguished scientists and six normative controls. Overall, there were significant differences ( p < 0.001) between the comparison groups in both minicolumnar width (CW) and mean cell spacing (MCS). Although our scientists did not exhibit deficits in communication or interpersonal skills, the resultant minicolumnar phenotype bears similarity to that described for both autism and Asperger's syndrome. Computer modeling has shown that smaller columns account for discrimination among signals during information processing. A minicolumnar phenotype that provides for discrimination and/or focused attention may help explain the savant abilities observed in some autistic people and the intellectually gifted. |
| Databáze: | OpenAIRE |
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