Cryoballoon Ablation in Young Patients With Lone Paroxysmal Atrial Fibrillation
| Autor: | Maciej Wójcik, Heinz F. Pitschner, Thomas Neumann, Christian W. Hamm, Sergey Zaltsberg, Alexander Berkowitsch, Malte Kuniss |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Paroxysmal atrial fibrillation Cryosurgery Pulmonary vein Internal medicine Atrial Fibrillation medicine Humans cardiovascular diseases Angioplasty Balloon Coronary Atrial tachycardia Cryoballoon ablation business.industry Atrial fibrillation General Medicine Middle Aged medicine.disease Surgery Dronedarone Treatment Outcome cardiovascular system Cardiology Female medicine.symptom business Atrial flutter medicine.drug Cohort study |
| Zdroj: | Revista Española de Cardiología (English Edition). 67:558-563 |
| ISSN: | 1885-5857 |
| DOI: | 10.1016/j.rec.2013.11.024 |
| Popis: | Long-term efficacy following cryoballoon ablation of lone paroxysmal atrial fibrillation remains unknown. We describe long-term follow-up results of the single cryoballoon ablation procedure.Pulmonary vein isolation was performed in 103 patients (72 male; median age 52 years) with symptomatic lone paroxysmal atrial fibrillation. The end-point of this observational cohort study was first electrocardiogram-documented recurrence of arrhythmia (atrial fibrillation, atrial tachycardia, or atrial flutter) during the 5-year follow-up, in the absence of anti-arrhythmic treatment.Acute complete pulmonary vein isolation was achieved in 86% of the patients with a single cryoballoon. The 6-month, 1-year, and 5-year success rate after a single procedure was 94%, 91%, and 77%, respectively. Arrhythmia recurrence was observed in 24 cases at a median of 14.8 months [range, 8.0-16.8 months]. Thirteen symptomatic patients were well controlled on beta-blockers only. Seven symptomatic patients had anti-arrhythmic treatment (class IC in 5 patients; dronedarone in 2 patients) introduced during the blanking period. Two of them had early arrhythmia recurrence within the blanking period only; they were arrhythmia-free in further follow-up on dronedarone. The rate of complications was relatively low and included a 4.8% incidence of transient phrenic nerve palsy.A single cryoballoon ablation procedure for lone paroxysmal atrial fibrillation resulted in high rates of acute, medium-term, and long-term efficacy. The rate of complications is relatively low and includes a 4.8% incidence of transient phrenic nerve palsy. |
| Databáze: | OpenAIRE |
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