Healthy aging and disease

Autor: Pim van der Harst, Haidong Zhu, Matthew Belcher
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Telomerase
Heart disease
Parkinson's disease
SMOOTH-MUSCLE-CELLS
DHA
docosahexaenoic acid

heart failure
HEMODIALYSIS-PATIENTS
Disease
Review Article
CHF
chronic heart failure

TRF
telomeric repeat-binding factor

Bioinformatics
BLOOD MONONUCLEAR-CELLS
PD
Parkinson's disease

Degenerative disease
LDL
low-density lipoprotein

OXIDATIVE STRESS
telomere
Stem Cells
General Medicine
Alzheimer's disease
CHRONIC HEART-FAILURE
TERT
telomerase reverse transcriptase

Cardiovascular Diseases
CARDIOVASCULAR-DISEASE
CRP
C-reactive protein

AD
Alzheimer's disease

Senescence
medicine.medical_specialty
PBMC
peripheral blood mononuclear cell

S1
CVD
cardiovascular disease

telomerase
S5
SHR
spontaneous hypertensive rats

T1D
Type 1 diabetes

Aging-associated diseases
longevity
Internal medicine
Diabetes Mellitus
medicine
Humans
GENOME-WIDE ASSOCIATION
T2D
Type 2 diabetes

ENDOTHELIAL PROGENITOR CELLS
business.industry
aging
medicine.disease
EPA
eicosapentaenoic acid

Telomere
Endocrinology
Ageing
Chronic Disease
TERRA
telomeric repeat-containing RNA

atherosclerosis
REPEAT-CONTAINING RNA
business
ACEI
angiotensin-converting enzyme inhibitor

TERC
telomerase RNA component

REVERSE-TRANSCRIPTASE HTERT
Zdroj: Clinical Science (London, England : 1979)
ISSN: 0143-5221
DOI: 10.1042/cs20100385
Popis: Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.
Databáze: OpenAIRE