Paradoxical Computed Tomography-Derived Fractional Flow Reserve Changes Due to Vessel Morphology and Constituents
Autor: | Tsugu, Toshimitsu, Tanaka, Kaoru, Nagatomo, Yuji, De Maeseneer, Michel, Johan, De Mey |
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Přispěvatelé: | Brussels Heritage Lab, Radiology, Medical Imaging, Supporting clinical sciences, Anatomical Research and Clinical Studies, Artificial Intelligence supported Modelling in clinical Sciences, Body Composition and Morphology |
Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: |
Coronary Angiography/methods
Coronary Stenosis/diagnostic imaging Computed Tomography Angiography/methods fractional flow reserve myocardial Predictive Value of Tests Radiology Nuclear Medicine and imaging Humans Coronary Vessels/diagnostic imaging Constriction Pathologic Cardiology and Cardiovascular Medicine Tomography X-Ray Computed Coronary Artery Disease/pathology Severity of Illness Index |
DOI: | 10.5543/tkda.2022.02281 |
Popis: | Computed tomography-derived fractional flow reserve decreases from the proximal to the distal with coronary stenosis. According to the principles of fluid dynamics, paradoxical computed tomography-derived fractional flow reserve changes require an unconventional vessel mor-phology and specific site of the vessels with a high driving force. Therefore, only a few articles have reported a paradoxical increase of computed tomography-derived fractional flow reserve. We present a case report of marked computed tomography-derived fractional flow reserve elevation in the middle left anterior descending artery with a severe coronary stenosis. Computed tomography-derived fractional flow reserve was 0.94 just proximal to the stenotic lesion and decreased to 0.65 at the maximum stenosis area but recovered to 0.80 in the distal segment. We speculated that the vessel morphology could have caused a pressure recovery phenomenon, resulting in paradoxical computed tomography-derived fractional flow reserve changes. |
Databáze: | OpenAIRE |
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