Galactofuranose-rich heteropolysaccharide from Trebouxia sp., photobiont of the lichen Ramalina gracilis and its effect on macrophage activation
| Autor: | Marcello Iacomini, Dorly de Freitas Buchi, Lucimara M.C. Cordeiro, Simone M. de Oliveira |
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| Rok vydání: | 2007 |
| Předmět: |
Trebouxia
Male Magnetic Resonance Spectroscopy Lichens Polysaccharide Biochemistry Microbiology Mice Structural Biology Chlorophyta Polysaccharides Ramalina Macrophage Animals Lichen Molecular Biology Cells Cultured chemistry.chemical_classification biology Galactose General Medicine Macrophage Activation biology.organism_classification In vitro chemistry Macrophages Peritoneal Microscopy Electron Scanning |
| Zdroj: | International journal of biological macromolecules. 42(5) |
| ISSN: | 0141-8130 |
| Popis: | A structural study of the carbohydrates from Trebouxia sp., the algal symbiont of the lichen Ramalina gracilis demonstrated a galactofuranan-rich heteropolysaccharide, which was predominated by (1 → 5)linked galactofuranosyl units with side-chains in position 6 on approximately 11.0% of the units. The side-chains have very complex branched structures. This polysaccharide showed cell eliciting activity on peritoneal macrophages in vitro at all concentrations tested (1–150g/mL), and at 150g/mL an increase of 60% of macrophage activation in comparision to the control group was observed. A potential role of these carbohydrates in lichen recognition process is also discussed. © 2008 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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