Surgical Margin Mapping of Melanoma In Situ Using In Vivo Reflectance Confocal Microscopy Mosaics
| Autor: | Hillary Elwood, John R. Durkin, Catherine N. Tchanque-Fossuo, Alexander Rose, Naiara S Barbosa, Shelly Stepenaskie |
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| Rok vydání: | 2021 |
| Předmět: |
Reflectance confocal microscopy
Adult Male medicine.medical_specialty Surgical margin Skin Neoplasms Confocal Melanoma in situ Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Margin (machine learning) Medicine Humans Prospective Studies Stage (cooking) Melanoma Aged Microscopy Confocal business.industry One stage Margins of Excision General Medicine Middle Aged Mohs Surgery 030220 oncology & carcinogenesis Surgery Female Radiology Treatment time business Carcinoma in Situ |
| Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 47(5) |
| ISSN: | 1524-4725 |
| Popis: | Background Melanoma in situ (MIS) can have poorly defined borders and subclinical extension that makes margin control challenging. Reflectance confocal microscopy (RCM) is a promising noninvasive technique that can be used to assess subclinical spread. Objective To optimize surgical margins of histology-proven MIS using RCM mosaics. Materials and methods Prospective review of 22 patients with histology-proven MIS who underwent RCM margin mapping prior to staged excision, between August 1, 2018, and August 13, 2020, at the Department of Dermatology, University of New Mexico, School of Medicine. Results Twenty patients (91%) had tumor clearance on the first stage using a 3-mm surgical margin after confocal margin mapping. Conclusion Reflectance confocal microscopy margin mapping using the mosaic device tends to clear MIS in one stage, and the use of the handheld device may improve the accuracy for difficult anatomic areas. Current Procedural Terminology codes for RCM do not reflect the time required and complexity of the procedure. Reflectance confocal microscopy margin mapping prior to excision has the potential to decrease the number of stages needed for melanoma removal, reduce treatment time, and cost. |
| Databáze: | OpenAIRE |
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