Transplantation of Kidneys from Donors Whose Hearts Have Stopped Beating
| Autor: | David W. Gjertson, Cecka Jm, Paul I. Terasaki, Yong W. Cho |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Kidney animal structures Graft failure business.industry Urology musculoskeletal neural and ocular physiology Renal function General Medicine medicine.disease Kidney transplant Surgery Transplantation surgical procedures operative medicine.anatomical_structure cardiovascular system Medicine business Survival rate Kidney transplantation circulatory and respiratory physiology Kidney disease |
| Zdroj: | New England Journal of Medicine. 338:221-225 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm199801223380403 |
| Popis: | Background Attempts have recently been made to expand the number of cadaveric kidneys available for transplantation by using kidneys from donors without heartbeats in addition to those from brain-dead donors with beating hearts. We studied the efficacy of transplanting kidneys from donors without heartbeats on the basis of aggregate results from the Kidney Transplant Registry of the United Network for Organ Sharing. Methods We compared the early function and survival rates of 229 kidney grafts from donors without heartbeats with those of 8718 grafts from cadaveric donors with heartbeats. All transplantations were performed at 64 U.S. transplantation centers. Cox proportional-hazards analysis was used to evaluate 10 major risk factors for graft failure. Results The survival rate at one year was 83 percent for kidney grafts from donors without heartbeats, as compared with 86 percent for grafts from donors with heartbeats (P = 0.26). Among the kidneys from donors without heartbeats, the survival rate at one ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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