Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial
| Autor: | P Rohdewald, R. Stanislavov, V. Nikolova |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Randomization Urology Vasodilator Agents Blood Pressure Placebo Arginine law.invention Randomized controlled trial Double-Blind Method Erectile Dysfunction law Internal medicine medicine Humans Testosterone Flavonoids Aspartic Acid Neurotransmitter Agents Cross-Over Studies business.industry Plant Extracts Penile Erection Testosterone (patch) Middle Aged medicine.disease Crossover study Drug Combinations Endocrinology Erectile dysfunction Blood pressure Cholesterol Treatment Outcome Drug Therapy Combination Nitric Oxide Synthase Sexual function business |
| Zdroj: | International journal of impotence research. 20(2) |
| ISSN: | 1476-5489 |
| Popis: | In a randomly allocated, double-blind, placebo-controlled, crossover design, 50 patients with mild to moderate erectile dysfunction (ED) were treated for 1 month with placebo or a combination of L-arginine aspartate and Pycnogenol (Prelox). Patients reported sexual function from diaries. Testosterone levels and endothelial NO synthase (e-NOS) were monitored along with routine clinical chemistry. Intake of Pycnogenol for 1 month restored erectile function to normal. Intercourse frequency doubled. e-NOS in spermatozoa and testosterone levels in blood increased significantly. Cholesterol levels and blood pressure were lowered. No unwanted effects were reported. Prelox is a promising alternative to treat mild to moderate ED. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|