Association between Periodontitis and Aortic Calcification: A Cohort Study
| Autor: | Ying-lin Yu, Jun-rong Ma, Shu-na Li, Min-qi Liao, Shan Xu, Hong-en Chen, Shu-hong Dai, Xiao-lin Peng, Dan Zhao, Yan-mei Lou, Xiao-xuan Yu, Xu-ping Gao, Yan-hua Liu, Jun Liu, Xing-yao Ke, Zhao Ping, Li Wang, Chang-yi Wang, Fang-fang Zeng |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Angiology. 74:129-138 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/00033197221094713 |
| Popis: | The present study investigated the association between the presence of periodontitis and aortic calcification (AC) risk among Chinese adults. A total of 6059 individuals who underwent regular health check-ups and received a diagnosis of periodontitis between 2009 and 2016 were included. The outcome was AC, assessed by a chest low-dose spiral CT scan. Cox proportional hazards regression analysis was used to assess the association between periodontitis and AC risk after adjusting for several confounders. After a median follow-up period of 2.3 years (interquartile range: 1.03–4.97 years), 843 cases of AC were identified, with 532 (12.13%) and 311 (18.59%) patients in the non-periodontitis group and periodontitis group, respectively. Multivariate analyses demonstrated that, compared with those without periodontitis, the hazard ratio and 95% confidence interval for AC risk in participants with periodontitis was 1.18 (1.02–1.36) ( P = .025) in the fully adjusted model. Stratified analyses showed that the positive relationship between periodontitis and AC was more evident in males and participants interaction = .005 and .004, respectively). Our results show that the presence of periodontitis was positively associated with AC among Chinese adults, especially among males and younger participants. |
| Databáze: | OpenAIRE |
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