Facile synthesis of Cu N-lauroyl sarcosinate nanozymes with laccase-mimicking activity and identification of toxicity effects for

Autor: Fanwei Meng, Guofang Ma, Jiahe Qiu, Zhendong Fu, Jiaqing Yan, Lingping Wang
Rok vydání: 2022
Předmět:
Zdroj: RSC advances. 12(51)
ISSN: 2046-2069
Popis: Nanozyme is a material with enzyme-like catalytic activity, which has been widely used in environmental, antibacterial, and other fields of research. However, there are few reports on the toxicity of nanozymes. In this work, nanozymes co-assembled from sodium N-lauroyl sarcosinate (Ls) and Cu ions possess a Cu(i)-Cu(ii) electron transfer system similar to that of natural laccases. Reaction kinetic studies show that the catalyst follows a typical Michaelis-Menten model. Cu-N-lauroyl sarcosinate nanozyme (Cu-Ls NZ) possess excellent laccase-like activity to oxidize a variety of phenol-containing substrates, such as phenol, 4-iodophenol, and 2,4,5-trichlorophenol. To evaluate the toxicity of the material, the nematode
Databáze: OpenAIRE