Lymphatic vessel invasion in pathologic stage I and II non-small cell lung tumors
| Autor: | Hyun Woo Jeon, Young Pil Wang, Young-Du Kim, Jae Kil Park, Hyung Joo Park, Kyung Soo Kim, Keon Hyun Jo |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Oncology medicine.medical_specialty Lung Neoplasms Surgical oncology Carcinoma Non-Small-Cell Lung Internal medicine Diabetes mellitus medicine Carcinoma Lymphatic vessel Humans Neoplasm Invasiveness Lung Survival analysis Lymphatic Vessels Neoplasm Staging Retrospective Studies Lung cancer surgery business.industry Retrospective cohort study General Medicine Middle Aged Prognosis medicine.disease Survival Analysis medicine.anatomical_structure Female Surgery business |
| Zdroj: | Surgery Today. 45:1018-1024 |
| ISSN: | 1436-2813 0941-1291 |
| DOI: | 10.1007/s00595-014-1082-2 |
| Popis: | Tumor node-metastasis staging is essential for predicting the prognosis of patients with non-small cell lung cancer (NSCLC); however, its accuracy remains limited. The aim of this study was to establish the significant predictors of outcome for patients with pathologic stage I or II NSCLC. We reviewed the records of patients with pathologic stage I and II NSCLC retrospectively. After the exclusion of those who underwent sublobar resection, received neoadjuvant treatment, or died within 30 days of surgery, 271 patients treated between January, 2004 and December, 2010 were analyzed. We investigated whether lymphatic vessel invasion (LVI) grade was associated with prognosis in stage I or II NSCLC. The median age of the patients was 64 years. Of the 198 and 73 patients with pathologic stage I and stage II disease, respectively, 73 (26.9 %) had LVI. Thirteen patients had a high degree of LVI. Although LVI was not associated with overall survival (p = 0.13), a high degree of LVI was associated with poor survival (p |
| Databáze: | OpenAIRE |
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