Inflammation level and renal function injury in antineutrophil cytoplasmic antibody-associated vasculitis: a correlation with low albumin and high-density lipoprotein
| Autor: | Z Pei, Tingting Zeng, Yang Wu, Jiayi Huang, Yongjian Tian, Liming Tan, Jianlin Yu |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Clinical Biochemistry Renal function Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis Serum Albumin Human 030204 cardiovascular system & hematology Kidney Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine High-density lipoprotein Internal medicine Drug Discovery medicine Humans Aged Anti-neutrophil cytoplasmic antibody Inflammation Creatinine medicine.diagnostic_test biology business.industry Biochemistry (medical) C-reactive protein nutritional and metabolic diseases Middle Aged medicine.disease C-Reactive Protein chemistry 030220 oncology & carcinogenesis Erythrocyte sedimentation rate biology.protein Uric acid Female lipids (amino acids peptides and proteins) Lipoproteins HDL business Vasculitis |
| Zdroj: | Biomarkers in Medicine. 13:557-565 |
| ISSN: | 1752-0371 1752-0363 |
| DOI: | 10.2217/bmm-2018-0303 |
| Popis: | Aim: To explore the correlation of inflammation level and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis (AAV) patients with Alb and HDL. Materials & methods: Serum levels of Alb and HDL were measured, with AAV patients being grouped according to serum Alb and HDL levels, and indicators reflecting inflammation and renal injury were compared. Results: Serum levels of creatinine (Cr), uric acid and CRP and renal involvement rates were higher in lower Alb patients; Cr, CRP, renal and cardiovascular involvement rates in lower HDL patients were higher. Alb and HDL were negatively correlated with CRP and erythrocyte sedimentation rate. Conclusion: Serum Alb and HDL were good indictors for disease monitoring in AAV. |
| Databáze: | OpenAIRE |
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