Application of an Individual-Based Transmission Hazard Model for Estimation of Influenza Vaccine Effectiveness in a Household Cohort
| Autor: | Kyu Han Lee, Marisa C. Eisenberg, Ryan E. Malosh, Sophia Ng, Suzanne E. Ohmit, Joshua G. Petrie, Arnold S. Monto |
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| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Adolescent Practice of Epidemiology Epidemiology Influenza vaccine Cohort Studies 03 medical and health sciences 0302 clinical medicine Influenza Human Credible interval Humans Medicine 030212 general & internal medicine Child Proportional Hazards Models Family Characteristics Proportional hazards model business.industry Influenza A Virus H3N2 Subtype Age Factors Regression analysis Models Theoretical Virology Confidence interval 030104 developmental biology Influenza Vaccines Child Preschool Cohort Respiratory virus Female Epidemiologic Methods business Demography Cohort study |
| Zdroj: | American Journal of Epidemiology. 186:1380-1388 |
| ISSN: | 1476-6256 0002-9262 |
| Popis: | Household cohort studies are an important design for the study of respiratory virus transmission. Inferences from these studies can be improved through the use of mechanistic models to account for household structure and risk as an alternative to traditional regression models. We adapted a previously described individual-based transmission hazard (TH) model and assessed its utility for analyzing data from a household cohort maintained in part for study of influenza vaccine effectiveness (VE). Households with ≥4 individuals, including ≥2 children |
| Databáze: | OpenAIRE |
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