A case of topiramate-induced epistaxis

Autor: Antonella Alagna, Giovanni Polimeni, Achille P. Caputi, Francesco Cordici, Placido Bramanti, Rosario Grugno, Antongiulio Vitetta
Rok vydání: 2009
Předmět:
Zdroj: Current drug safety. 4(3)
ISSN: 2212-3911
Popis: The current case describes epistaxis in a patient treated with a daily regimen of topiramate 100mg for migraine. The patient had not a past medical history of nosebleeds and laboratory parameters were within normal ranges. She was then advised to withdraw topiramate, and the epistaxis resolved within 12 hours after its discontinuation. Since then, the patient never complained other blood clotting disorders. The potential antiplatelet activity of topiramate is discussed.
Databáze: OpenAIRE