A case of topiramate-induced epistaxis
Autor: | Antonella Alagna, Giovanni Polimeni, Achille P. Caputi, Francesco Cordici, Placido Bramanti, Rosario Grugno, Antongiulio Vitetta |
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Rok vydání: | 2009 |
Předmět: |
Pharmacology
Topiramate Adult Blood Platelets Migraine without Aura Past medical history Blood clotting business.industry Blood clotting disorders Fructose Toxicology medicine.disease Discontinuation Regimen Epistaxis Neuroprotective Agents Migraine Anesthesia medicine Humans Pharmacology (medical) Female business medicine.drug |
Zdroj: | Current drug safety. 4(3) |
ISSN: | 2212-3911 |
Popis: | The current case describes epistaxis in a patient treated with a daily regimen of topiramate 100mg for migraine. The patient had not a past medical history of nosebleeds and laboratory parameters were within normal ranges. She was then advised to withdraw topiramate, and the epistaxis resolved within 12 hours after its discontinuation. Since then, the patient never complained other blood clotting disorders. The potential antiplatelet activity of topiramate is discussed. |
Databáze: | OpenAIRE |
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