Postictal Psychosis in Temporal Lobe Epilepsy
| Autor: | Ivo Podreka, Susanne Asenbaum, Christoph Baumgartner, Uwe Pietrzyk, Helmut Lucht, Fritz Leutmezer, Norbert Benda, Claude Back |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Psychosis Neurocognitive Disorders Video Recording Hyperemia Electroencephalography Temporal lobe Central nervous system disease Epilepsy Epilepsy Complex Partial Technetium Tc 99m Exametazime Risk Factors medicine Humans Ictal Dominance Cerebral Monitoring Physiologic Tomography Emission-Computed Single-Photon medicine.diagnostic_test medicine.disease Temporal Lobe Frontal Lobe Epilepsy Temporal Lobe Neurology Frontal lobe Cerebral blood flow Female Neurology (clinical) Psychology Neuroscience |
| Zdroj: | Epilepsia. 44:582-590 |
| ISSN: | 1528-1167 0013-9580 |
| DOI: | 10.1046/j.1528-1157.2003.32802.x |
| Popis: | Summary: Purpose: Postictal psychosis is a well-known complication, occurring especially in patients with temporal lobe epilepsy. It usually runs a benign course. The literature on this topic is sparse, and the underlying pathogenic mechanisms are not known. Methods: We report five patients with temporal lobe epilepsy in whom postictal psychosis developed during the course of video-EEG monitoring; they were studied with hexamethyl-propyleneamine-oxime single-photon emission computed tomography (HMPAO-SPECT) during and after the psychotic event. Results: In comparison to the interictal state, all SPECT scans obtained during postictal psychosis were remarkable for bifrontal and bitemporal hyperperfusion patterns. Some studies also demonstrated unilateral left lateral frontal hyperperfusion. These cortical blood-flow patterns appeared to be distinct from those obtained during complex partial seizures. Conclusions: Our data suggest that postictal psychoses in patients with temporal lobe epilepsy are associated with hyperactivation of both temporal and frontal lobe structures. This hyperperfusion may reflect ongoing (subcortical) discharges, active inhibitory mechanisms that terminate the seizure, or simply a dysregulation of cerebral blood flow. |
| Databáze: | OpenAIRE |
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