Cardiovascular adaptations in rats submitted to a resistance-training model
| Autor: | Valerio G, Barauna, Miguel Luis, Batista, Miguel Luis B, Junior, Luis Fernando B P, Costa Rosa, Dulce E, Casarini, José Eduardo, Krieger, Edilamar M, Oliveira |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
Weight Lifting Physiology Diastole Blood Pressure Left ventricular hypertrophy Cardiovascular Physiological Phenomena Weight-Bearing Random Allocation Catecholamines Physiology (medical) Internal medicine One-repetition maximum Physical Conditioning Animal Heart rate Adrenal Glands medicine Animals Rats Wistar Muscle Skeletal Pharmacology Atrium (architecture) business.industry Body Weight Heart Organ Size medicine.disease Electric Stimulation Rats Endocrinology medicine.anatomical_structure Blood pressure Ventricle Models Animal Catecholamine business medicine.drug |
| Zdroj: | Clinical and experimental pharmacologyphysiology. 32(4) |
| ISSN: | 0305-1870 |
| Popis: | 1. The present study sought to evaluate cardiovascular adaptations, such as blood pressure (BP), heart rate (HR) and cardiac hypertrophy, to resistance training (RT) in a rat model. 2. The training protocol consisted of four sets of 10-12 repetitions of the squat exercise performed at 65-75% of one repetition maximum (1RM) over 4 weeks. Animals were randomly divided into three groups: control (n = 8, CO), electrically stimulated (n = 8, ES) and trained (n = 8, TR; also electrically stimulated). Blood pressure and HR were measured by a direct method in conscious rats after the training period. 3. All groups began with similar 1RM and 1RM/bodyweight (BW) ratio, however, at the end of the protocol only the TR group was different from the beginning (56% and 50%, respectively; both P < 0.01). The CO and ES groups had similar values for cardiac chambers weight/BW ratio, HR and diastolic, systolic and mean BP. Left ventricular hypertrophy (LVH) determined by the left ventricle (LV) weight/BW ratio was increased in the TR group (12%) when compared to CO (P < 0.01) or ES groups (P < 0.01). No changes were found in the weights of the atrium or right ventricle. Diastolic (14%) and mean BP (13%) were lower in the TR group (P < 0.05), whereas systolic BP and HR remained unchanged. 4. Collectively these results demonstrate that the rat RT model used is associated with significant development of cardiac hypertrophy and lowering of resting BP. These cardiovascular adaptations seem to a result of the training exercise and not influenced by stress since circulating catecholamine levels and adrenal gland weights remained unchanged in all groups. |
| Databáze: | OpenAIRE |
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