Effect of Aramine on the Survival of Dogs Subjected to Hemorrhagic Hypotension

Autor:	Herbert E. Kaufman, Stanley J. Sarnoff
Rok vydání:	1954
Předmět:	medicine.medical_specialty Treated group Physiology business.industry Hemorrhage Hemorrhagic hypotension Surgery Dogs Anesthesia medicine Animals Metaraminol Hypotension Sympathomimetics Cardiology and Cardiovascular Medicine business medicine.drug
Zdroj:	Circulation Research. 2:420-423
ISSN:	1524-4571 0009-7330
DOI:	10.1161/01.res.2.5.420
Popis:	One group of 19 control dogs and other group of 20 "treated" dogs were bled into hemorrhagic hypotension after Nembutal anesthesia and their arterial pressures controlled at 40 mm. Hg for an average period of one hour and fifteen minutes. Neither group had further blood depletion, or replacement, for an additional 1 hour and 39 minutes, but the treated group received Aramine. Reinfusion was performed after an oligemic period totaling 2 hours and 54 minutes. Of the dogs in the control group, 10.5 per cent survived; 50 per cent of the treated dogs survived.
Databáze:	OpenAIRE
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