Seroprevalence of markers of hepatitis C virus exposure and associated factors in adults aged 18-39 years in the Arctic Russian city of Arkhangelsk: a cross-sectional study

Autor: A. L. Sannikov, Tatiana Viktorovna Balaeva, Andrei M. Grjibovski, Elise Klouman, O. V. Samodova
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Health (social science)
Epidemiology
Cross-sectional study
Hepacivirus
medicine.disease_cause
Antibodies
Viral

0302 clinical medicine
Risk Factors
Seroepidemiologic Studies
Surveys and Questionnaires
Global health
030212 general & internal medicine
Original Research Article
hepatitis c
Substance Abuse
Intravenous

education.field_of_study
seroprevalence
Arctic Regions
General Medicine
Hepatitis C
population-based study
Female
0305 other medical science
Viral hepatitis
Adult
associated factors
medicine.medical_specialty
russia
lcsh:Arctic medicine. Tropical medicine
Adolescent
lcsh:RC955-962
Hepatitis C virus
Population
03 medical and health sciences
Young Adult
Environmental health
medicine
hcv
Seroprevalence
Humans
Blood Transfusion
VDP::Medisinske Fag: 700
education
injecting drug use
030505 public health
business.industry
Public health
Public Health
Environmental and Occupational Health

medicine.disease
VDP::Medical disciplines: 700
Cross-Sectional Studies
Immunoglobulin M
Immunoglobulin G
business
Zdroj: International Journal of Circumpolar Health, Vol 78, Iss 1 (2019)
International Journal of Circumpolar Health
Popis: Hepatitis C, caused by the hepatitis C virus (HCV), is a major public health issue in Russia. The aim of our study was to assess the seroprevalence of markers of HCV exposure and factors associated with HCV seropositivity among the general population aged 18–39 years in the city of Arkhangelsk, Northwest Russia. A social research agency applied a quota sampling method to recruit study participants using cell phone numbers. All participants (n = 1243) completed a self-administered questionnaire and provided a blood sample. Sixty-five participants (5.2%, 95% confidence interval [CI] 4.9–5.5) tested positive for HCV IgM+G antibodies, and of these, 55 (84.6%) did not know that they were exposed to HCV. In multivariable logistic regression analysis, HCV seropositivity was significantly associated with older age, a history of injecting drug use, and having ever received a blood transfusion. To reach the goal of the World Health Organisation’s Global Health Sector Strategy on Viral Hepatitis, regional preventive programmes should include measures to reduce injecting drug use as well as scaling up harm-reduction and treatment programs for drug addicts.
Databáze: OpenAIRE