Successful intensive lipid-lowering therapy using atorvastatin stabilizes coronary artery plaque as assessed by multi-detector row computed tomography
| Autor: | Keijiro Saku, Hideya Niimura, Ryoko Mitsutake, Shin-ichiro Miura, Akira Kawamura, Keisuke Okamura |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Percutaneous Atorvastatin medicine.medical_treatment Coronary Artery Disease Angina Pectoris Angina Lesion Coronary artery disease Internal medicine Coronary stent Internal Medicine medicine Humans Pyrroles cardiovascular diseases business.industry Anticholesteremic Agents Coronary Stenosis Stent General Medicine medicine.disease medicine.anatomical_structure Treatment Outcome Heptanoic Acids cardiovascular system Cardiology Radiology medicine.symptom business Tomography X-Ray Computed medicine.drug Artery Follow-Up Studies |
| Zdroj: | Internal medicine (Tokyo, Japan). 46(12) |
| ISSN: | 1349-7235 |
| Popis: | A 35-year-old male was diagnosed as angina pectoris and showed severe stenosis with soft plaque in the proximal segment of the left anterior descending (LAD) coronary artery as detected by multi-detector row computed tomography (MDCT). Although percutaneous coronary stent implantation to the LAD lesion was performed, soft plaque remained in the proximal lesion of the stent. Atorvastatin increased the coronary plaque density at the 6-month follow-up MDCT examination, and the low-density lipoprotein cholesterol level fell from 141 to 63 mg/dl after 6 months. This case may indicate that assessment of the shape or composition of coronary plaque by MDCT is a useful strategy for judging the effects of intensive lipid-lowering therapy using statin. |
| Databáze: | OpenAIRE |
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