Do sex differences in the prevalence of ECG abnormalities vary across ethnic groups living in the Netherlands? A cross-sectional analysis of the population-based HELIUS study
Autor: | Jan A. Kors, Ron J.G. Peters, C. Cato ter Haar, Hanno L. Tan, Marieke B. Snijder, Renee Bolijn, Irene G. M. van Valkengoed, Ralf E. Harskamp, Anton E. Kunst, Pieter G. Postema |
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Přispěvatelé: | General practice, ACS - Heart failure & arrhythmias, APH - Personalized Medicine, Cardiology, APH - Health Behaviors & Chronic Diseases, APH - Methodology, ACS - Atherosclerosis & ischemic syndromes, Public and occupational health, APH - Global Health, ACS - Diabetes & metabolism, Medical Informatics |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent Cross-sectional study Population Ethnic group Disease Cardiovascular Medicine 030204 cardiovascular system & hematology Logistic regression Ghana Asymptomatic Electrocardiography Young Adult 03 medical and health sciences 0302 clinical medicine Epidemiology Ethnicity Prevalence medicine Humans 030212 general & internal medicine education Minority Groups pacing & electrophysiology Aged Netherlands cardiac epidemiology Sex Characteristics education.field_of_study business.industry public health General Medicine Middle Aged 3. Good health Cross-Sectional Studies Cohort Medicine Female epidemiology medicine.symptom business Demography |
Zdroj: | BMJ open, 10(9):e039091. BMJ Publishing Group BMJ Open BMJ Open, 10(9):e039091. BMJ Publishing Group BMJ Open, Vol 10, Iss 9 (2020) |
ISSN: | 2044-6055 |
Popis: | ObjectivesMajor ECG abnormalities have been associated with increased risk of cardiovascular disease (CVD) burden in asymptomatic populations. However, sex differences in occurrence of major ECG abnormalities have been poorly studied, particularly across ethnic groups. The objectives were to investigate (1) sex differences in the prevalence of major and, as a secondary outcome, minor ECG abnormalities, (2) whether patterns of sex differences varied across ethnic groups, by age and (3) to what extent conventional cardiovascular risk factors contributed to observed sex differences.DesignCross-sectional analysis of population-based study.SettingMulti-ethnic, population-based Healthy Life in an Urban Setting cohort, Amsterdam, the Netherlands.Participants8089 men and 11 369 women of Dutch, South-Asian Surinamese, African Surinamese, Ghanaian, Turkish and Moroccan origin aged 18–70 years without CVD.Outcome measuresAge-adjusted and multivariable logistic regression analyses were performed to study sex differences in prevalence of major and, as secondary outcome, minor ECG abnormalities in the overall population, across ethnic groups and by age-groups (18–35, 36–50 and >50 years).ResultsMajor and minor ECG abnormalities were less prevalent in women than men (4.6% vs 6.6% and 23.8% vs 39.8%, respectively). After adjustment for conventional risk factors, sex differences in major abnormalities were smaller in ethnic minority groups (OR ranged from 0.61 in Moroccans to 1.32 in South-Asian Surinamese) than in the Dutch (OR 0.49; 95% CI 0.36 to 0.65). Only in South-Asian Surinamese, women did not have a lower odds than men (OR 1.32; 95% CI 0.96 to 1.84). The pattern of smaller sex differences in ethnic minority groups was more pronounced in older than in younger age-groups.ConclusionsThe prevalence of major ECG abnormalities was lower in women than men. However, sex differences were less apparent in ethnic minority groups. Conventional risk factors did not contribute substantially to observed sex differences. |
Databáze: | OpenAIRE |
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