Cardiovascular risk and validation of cardiovascular risk prediction functions in a cohort of patients with type 2 diabetes followed for 10 years in Badajoz (SPAIN). AN observational study
| Autor: | Lourdes Cañón-Barroso, Juan Ignacio Calvo-Hueros, Francisco Buitrago, José Antonio Morales-Gabardino |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Longitudinal study Endocrinology Diabetes and Metabolism Population Type 2 diabetes Risk Assessment Risk Factors Internal medicine Diabetes mellitus Internal Medicine medicine Humans Longitudinal Studies education education.field_of_study Nutrition and Dietetics Framingham Risk Score business.industry Incidence (epidemiology) Middle Aged medicine.disease Diabetes Mellitus Type 2 Cardiovascular Diseases Heart Disease Risk Factors Spain Cohort Observational study Female Family Practice business |
| Zdroj: | Primary care diabetes. 15(1) |
| ISSN: | 1878-0210 |
| Popis: | To analyse whether diabetes behaves as an equivalent of coronary risk and assess the performance of the original and REGICOR Framingham functions in a cohort of patients with type 2 diabetes observed for 10 years in primary care practices in Badajoz, Spain.Observational, longitudinal study. A total of 643 patients (mean age 64.0 years, 55.7% women), without evidence of cardiovascular disease were studied. We assessed the incidence of cardiovascular events and the patients' 10-year coronary risk predicted-values at the time of their recruitment.The actual incidence rate of coronary events was 14.5% (15.1% in women and 13.7% in men, p = 0.616). Patients who suffered coronary events were older (66.3 vs 63.6 years, p0.05), had higher total cholesterol (236.3 vs 219.5 mg/dl, p0.01), fasting plasma glucose levels (177.6 vs 159.8 mg/dl, p0.01), glycated haemoglobin (7.3 vs 6.7%, p0.05) and also higher prevalence of high blood pressure, dyslipidemia and chronic renal disease. The original Framingham equation overpredicted risk by 88%, whereas the REGICOR Framingham function underpredicted risk by 24%.Diabetes in our cohort does not behave as a coronary heart disease equivalent and both the original and REGICOR Framingham coronary risk functions have little utility in a diabetic population. |
| Databáze: | OpenAIRE |
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