Comparative analysis of LTR and structural genes in an equine infectious anemia virus strain isolated from a feral horse in Japan
| Autor: | Frank R. Cook, Yoshitaka Goto, Wei Zhu, Takeshi Haga, Yoichiro Horii, Junzo Norimine, Naoaki Misawa, Jianbao Dong |
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| Rok vydání: | 2014 |
| Předmět: |
Genes
Viral animal diseases viruses Molecular Sequence Data Genetic analysis Genome Virus Equine infectious anemia Japan Proviruses Virology Animals Horses Conserved Sequence Genetics biology Molecular epidemiology Base Sequence Structural gene Terminal Repeat Sequences Genetic Variation General Medicine Sequence Analysis DNA biology.organism_classification Long terminal repeat Equine Infectious Anemia Lentivirus Sequence Alignment Infectious Anemia Virus Equine |
| Zdroj: | Archives of virology. 159(12) |
| ISSN: | 1432-8798 |
| Popis: | Although equine infectious anemia virus (EIAV) poses a major threat to the equine industry worldwide, the molecular epidemiology of this virus is poorly understood. Recently, an EIAV strain (EIAVMiyazaki2011-A) representing a new monophyletic group was discovered in feral horses in southern Japan. In the present study, the EIAVMiyazaki2011-A proviral genome is compared with evolutionarily divergent EIAV isolates to investigate conservation of functional elements or motifs within the long terminal repeats (LTRs) and structural genes. This analysis represents a significant step forward in increasing understanding of the molecular conservation and variation between geographically distinct strains of this equine lentivirus. |
| Databáze: | OpenAIRE |
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