Human Fitting Studies of Cleveland Clinic Continuous-Flow Total Artificial Heart
| Autor: | Kiyotaka Fukamachi, Vincent B. Cruz, Gengo Sunagawa, Nader Moazami, Nicole Byram, David J. Horvath, Jamshid H. Karimov, Robert J. Steffen, Leonard A.R. Golding |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Models Anatomic medicine.medical_specialty Biomedical Engineering Biophysics Thoracic Cavity Bioengineering Inflow Article law.invention Biomaterials Imaging Three-Dimensional law Artificial heart medicine Body Size Humans Heart-Assist Devices Heart Failure Body surface area business.industry Thoracic cavity Equipment Design General Medicine Middle Aged medicine.disease Surgery medicine.anatomical_structure Heart failure Circulatory system cardiovascular system Female Outflow Nuclear medicine business |
| Zdroj: | ASAIO Journal. 61:424-428 |
| ISSN: | 1058-2916 |
| DOI: | 10.1097/mat.0000000000000219 |
| Popis: | Implantation of mechanical circulatory support devices is challenging, especially in patients with a small chest cavity. We evaluated how well the Cleveland Clinic continuous-flow total artificial heart (CFTAH) fit the anatomy of patients about to receive a heart transplant. A mock pump model of the CFTAH was rapid-prototyped using biocompatible materials. The model was brought to the operative table, and the direction, length, and angulation of the inflow/outflow ports and outflow conduits were evaluated after the recipient's ventricles had been resected. Thoracic cavity measurements were based on preoperative computed tomographic data. The CFTAH fit well in all five patients (height, 170 ± 9 cm; weight, 75 ± 24 kg). Body surface area was 1.9 ± 0.3 m (range, 1.6-2.1 m). The required inflow and outflow port orientation of both the left and right housings appeared consistent with the current version of the CFTAH implanted in calves. The left outflow conduit remained straight, but the right outflow direction necessitated a 73 ± 22 degree angulation to prevent potential kinking when crossing over the connected left outflow. These data support the fact that our design achieves the proper anatomical relationship of the CFTAH to a patient's native vessels. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|