Characterization of human stellate cell activation-associated protein and its expression in human liver
Autor: | Katsutoshi Yoshizato, Norifumi Kawada, Dan Bach Kristensen, Chise Tateno, Kazuki Nakatani, Shuichi Seki, Masanobu Obara, Miho Shiokawa, Kinji Asahina |
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Rok vydání: | 2002 |
Předmět: |
Hemeproteins
DNA Complementary Hepatitis Viral Human Liver cytology Molecular Sequence Data Biophysics Biochemistry law.invention chemistry.chemical_compound Exon Structural Biology law Complementary DNA Genetics Humans Amino Acid Sequence Heme Gene Messenger RNA Chemistry Cytoglobin Exons Immunohistochemistry Molecular biology Recombinant Proteins Globins Hepatitis Autoimmune Liver Peroxidases Recombinant DNA Hepatic stellate cell Sequence Alignment Chromosomes Human Pair 17 |
Zdroj: | Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1577:471-475 |
ISSN: | 0167-4781 |
Popis: | This study cloned cDNA of human homologue (hSTAP) of rat stellate cell activation-associated protein (rSTAP). hSTAP gene is on chromosome 17q and is composed of four exons. Various types of cells including hepatic stellate cells expressed hSTAP mRNA. Recombinant hSTAP was a heme protein with the activity of peroxidase. hSTAP can be used as a marker of quiescent stellate cells in human liver. |
Databáze: | OpenAIRE |
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