Duodenal Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report
| Autor: | Seong Ho Hong, Dong Hun Lee, Seong Bo Yoon, Jung Han Kim, Joo Hyun Jang, Il Hyun Baek, Kyung Hee Woo |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Vincristine
Pathology medicine.medical_specialty Lymphoepithelial lesion Duodenum Prednisolone Case Report Helicobacter Infections hemic and lymphatic diseases Biopsy medicine Humans Chemotherapy MALT lymphoma Cyclophosphamide Aged Helicobacter pylori medicine.diagnostic_test biology business.industry Antineoplastic Protocols Lymphoma B-Cell Marginal Zone medicine.disease biology.organism_classification Lymphoma medicine.anatomical_structure Lymphatic system Female business medicine.drug |
| Zdroj: | The Korean Journal of Internal Medicine |
| ISSN: | 1226-3303 |
| DOI: | 10.3904/kjim.2007.22.4.296 |
| Popis: | Primary duodenal mucosa associated lymphoid tissue (MALT) lymphoma is very rare, and little is known about its clinical course or effective treatment. We describe a case of primary duodenal MALT lymphoma that was resistant to Helicobacter pylori (H. pylori) eradication and regressed after chemotherapy with cyclophosphamide, vincristine, and prednisolone (CVP). A 71-year-old woman was referred to our department because of epigastric pain and dyspepsia. Gastroduodenoscopy revealed an irregular mucosal nodular lesion with ulceration extending from the bulb to the second portion of the duodenum. Histopathological examination of a biopsy specimen disclosed low-grade MALT lymphoma composed of atypical lymphoid cells with lymphoepithelial lesion. Abdominal CT scans revealed 0.5 to 1.5 cm lymph nodes in the peritoneal cavity, suggestive of lymph node metastasis. We successfully eradicated H. pylori but did not see signs of remission. We administered systemic CVP chemotherapy every 3 weeks. After 6 courses of CVP, the patient achieved complete remission and was followed up without recurrence for about a year. |
| Databáze: | OpenAIRE |
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