The genome sequence of a novel simian adenovirus in a chimpanzee reveals a close relationship to human adenoviruses
| Autor: | Quan Shen, Wen Zhang, Shixing Yang, Bin Ni, Xingli Fu, Yan Wang, Wei Liu, Chenglin Zhou, Rongmei Fei, Xiaochun Wang, Hua Tian, Shengxia Chen |
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| Rok vydání: | 2014 |
| Předmět: |
endocrine system
Pan troglodytes animal diseases viruses Genome Viral Biology Simian Genome law.invention law Virology Animals Humans Clade Phylogeny Genetics Whole genome sequencing Phylogenetic tree Adenoviruses Human Strain (biology) virus diseases General Medicine biology.organism_classification eye diseases Ape Diseases GenBank Recombinant DNA Adenoviruses Simian |
| Zdroj: | Archives of Virology. 159:1765-1770 |
| ISSN: | 1432-8798 0304-8608 |
| Popis: | Recently, several reports have revealed that some simian adenoviruses (AdVs) strains show a close relationship to human AdVs. In the present study, a simian AdV strain named SAdV-ch1 was detected in chimpanzees in China, and its complete genome was determined. Phylogenetic analysis revealed SAdV-ch1 clustering in a clade that was separate from all of the other simian AdVs but genetically close to a human AdV strain, HAdV-18 (GenBank no. GU191019), sharing 92.5 % sequence identity with it. Recombination analysis provided evidence that a recombination event had occurred between SAdV-ch1 and HAdV-61 (JF964962), where SAdV-ch1 exchanged partial of its hexon gene segment with HAdV-61, leading to the recombinant HAdV-31 (AM749299). |
| Databáze: | OpenAIRE |
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