Prenatal diagnosis of Fanconi anemia
| Autor: | Z. Ben-Zur, Arleen D. Auerbach, H. Yaffe, G. Kohn, Asher Ornoy, M. Golbus, Meira Shaham, Ruth Voss, Judy Arnon |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Cytodiagnosis Diepoxybutane Prenatal diagnosis chemistry.chemical_compound Pregnancy Fanconi anemia Genetics medicine Chromosomes Human Humans Abnormalities Multiple reproductive and urinary physiology Genetics (clinical) Chromosome Aberrations Fetus Obstetrics business.industry Aborted Fetus Anemia Aplastic medicine.disease Fanconi Anemia chemistry embryonic structures Immunology Amniocentesis Butanes Carcinogens Epoxy Compounds Female Chromosome breakage business Fetal skin |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1399-0004 0009-9163 |
| DOI: | 10.1111/j.1399-0004.1981.tb01828.x |
| Popis: | Prenatal diagnosis was performed on a fetus at risk for Fanconi anemia. A high spontaneous (0.30 breaks/cell) and diepoxybutane-induced (0.69 breaks/cell) chromosome breakage rate indicated an affected fetus and the pregnancy was terminated. The anatomic findings in the aborted fetus together with cytogenetic findings in cultured fetal skin fibroblasts confirmed the prenatal diagnosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text