Association Between Cortisol to DHEA-s Ratio and Sickness Absence in Japanese Male Workers
| Autor: | Yasuhito Fujii, Jiro Takaki, Toshiyo Taniguchi, Kumi Hirokawa, Akizumi Tsutsumi |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male endocrine system medicine.medical_specialty Hydrocortisone Health Behavior 050105 experimental psychology Young Adult 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dehydroepiandrosterone sulfate Surveys and Questionnaires Internal medicine medicine Humans 0501 psychology and cognitive sciences Prospective cohort study Applied Psychology Dehydroepiandrosterone Sulfate Proportional hazards model business.industry 05 social sciences Hazard ratio Confounding Middle Aged Confidence interval Endocrinology chemistry Female Sick Leave business hormones hormone substitutes and hormone antagonists 030217 neurology & neurosurgery Blood sampling Hormone |
| Zdroj: | International Journal of Behavioral Medicine. 25:362-367 |
| ISSN: | 1532-7558 1070-5503 |
| DOI: | 10.1007/s12529-017-9700-1 |
| Popis: | This study aimed to investigate the association between serum levels of cortisol and dehydroepiandrosterone sulfate (DHEA-s) and sickness absence over 2 years in Japanese male workers. A baseline survey including questions about health behavior, along with blood sampling for cortisol and DHEA-s, was conducted in 2009. In total, 429 men (mean ± SD age, 52.9 ± 8.6 years) from whom blood samples were collected at baseline were followed until December 31, 2011. The hazard ratios (HR) and 95% confidence intervals (CI) for sickness absence were calculated using a Cox proportional hazard model, adjusted for potential confounders. Among 35 workers who took sickness absences, 31 had physical illness. A high cortisol to DHEA-s ratio increased the risk of sickness absence (crude HR = 2.68, 95% CI 1.12–6.41; adjusted HR = 3.33, 95% CI 1.35–8.20). The cortisol to DHEA-s ratio was linearly associated with an increased risk of sickness absence (p for trend |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink