Preparation of Tetrasubstituted Furans via Intramolecular Wittig Reactions with Phosphorus Ylides as Intermediates

Autor:	Yi Wun Jhang, Wenwei Lin, Tzu Ting Kao, Siang En Syu
Rok vydání:	2010
Předmět:	Molecular Structure Phosphorus Organic Chemistry chemistry.chemical_element Stereoisomerism Biochemistry chemistry.chemical_compound Organophosphorus Compounds chemistry Intramolecular force Wittig reaction Organic chemistry Tributylphosphine Physical and Theoretical Chemistry Furans
Zdroj:	Organic Letters. 12:3066-3069
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol101080q
Popis:	Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::543b81200f43994630a6eaf2c2eae5c3 https://doi.org/10.1021/ol101080q Zobrazit plný text záznamu