Wireless, battery-free, flexible, miniaturized dosimeters monitor exposure to solar radiation and to light for phototherapy
| Autor: | Amnahir E. Peña-Alcántara, Shuai Xu, Rafal M. Pielak, Philipp Gutruf, Pinghung Wei, Jeonghyun Kim, Jean Won Kwak, Manish Patel, Carey Gaede, June K. Robinson, Anthony Banks, Hitoshi Araki, John A. Rogers, Yunzhou Shi, Guive Balooch, Yeojeong Yun, Kyu-Tae Lee, Derrick Rollo, Seung Yun Heo |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Ultraviolet Rays Computer science Electromagnetic spectrum Cumulative Exposure Context (language use) 02 engineering and technology Article 03 medical and health sciences Electric Power Supplies Radiation Monitoring Intensive Care Units Neonatal Intensive care Electronic engineering Humans Dosimetry Sunlight Miniaturization Dosimeter Radiation Dosimeters Infant Newborn General Medicine Phototherapy Radiation Exposure 021001 nanoscience & nanotechnology 030104 developmental biology Radio frequency 0210 nano-technology Wireless Technology |
| Zdroj: | Science Translational Medicine. 10 |
| ISSN: | 1946-6242 1946-6234 |
| DOI: | 10.1126/scitranslmed.aau1643 |
| Popis: | Exposure to electromagnetic radiation can have a profound impact on human health. Ultraviolet (UV) radiation from the sun causes skin cancer. Blue light affects the body’s circadian melatonin rhythm. At the same time, electromagnetic radiation in controlled quantities has beneficial use. UV light treats various inflammatory skin conditions, and blue light phototherapy is the standard of care for neonatal jaundice. Although quantitative measurements of exposure in these contexts are important, current systems have limited applicability outside of laboratories because of an unfavorable set of factors in bulk, weight, cost, and accuracy. We present optical metrology approaches, optoelectronic designs, and wireless modes of operation that serve as the basis for miniature, low-cost, and battery-free devices for precise dosimetry at multiple wavelengths. These platforms use a system on a chip with near-field communication functionality, a radio frequency antenna, photodiodes, supercapacitors, and a transistor to exploit a continuous accumulation mechanism for measurement. Experimental and computational studies of the individual components, the collective systems, and the performance parameters highlight the operating principles and design considerations. Evaluations on human participants monitored solar UV exposure during outdoor activities, captured instantaneous and cumulative exposure during blue light phototherapy in neonatal intensive care units, and tracked light illumination for seasonal affective disorder phototherapy. Versatile applications of this dosimetry platform provide means for consumers and medical providers to modulate light exposure across the electromagnetic spectrum in a way that can both reduce risks in the context of excessive exposure and optimize benefits in the context of phototherapy. |
| Databáze: | OpenAIRE |
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