Waitlist and posttransplantation outcomes of lean individuals with nonalcoholic fatty liver disease

Autor: Pedro Ochoa‐Allemant, Hirsh D. Trivedi, Behnam Saberi, Alan Bonder, Zachary P. Fricker
Rok vydání: 2023
Předmět:
Zdroj: Liver Transplantation. 29:145-156
ISSN: 1527-6465
DOI: 10.1002/lt.26531
Popis: Lean individuals with nonalcoholic fatty liver disease (NAFLD) represent a subset of patients with a distinct risk factor profile. We assessed the association between body mass index (BMI) on waitlist and postliver transplantation (LT) outcomes among these patients. We retrospectively analyzed the United Network for Organ Sharing data, including adult patients with NAFLD listed for LT between February 27, 2002, and June 30, 2020. We first used competing risk analyses to estimate the association of BMI with waitlist removal due to death or clinical deterioration. We then conducted Kaplan-Meier estimates and Cox regression models to determine the impact of weight change during the waiting list on all-cause mortality and graft failure after LT. Patients with normal weight (BMI 18.5-24.9 kg/m
Databáze: OpenAIRE