Respiratory Impairment in Workers Exposed to 'Safe' Levels of Toluene Diisocyanate (TDI)
| Autor: | Leonard D. Pagnotto, Raymond L. H. Murphy, John M. Peters, James L. Whittenberger |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
medicine.medical_specialty
Time Factors Respiratory impairment Respiratory Tract Diseases Positive correlation Asymptomatic chemistry.chemical_compound medicine Humans Environmental Chemistry Respiratory system Cyanates General Environmental Science Morning Toluene diisocyanate business.industry Age Factors Public Health Environmental and Occupational Health Surgery Occupational Diseases chemistry Spirometry Anesthesia Maximum Allowable Concentration medicine.symptom business |
| Zdroj: | Archives of Environmental Health: An International Journal. 20:364-367 |
| ISSN: | 0003-9896 |
| DOI: | 10.1080/00039896.1970.10665605 |
| Popis: | Workers in a factory producing polyurethane foam have been studied at six-month intervals for a period of 18 months. On each of the four surveys the forced expiratory volume in one second (FEV1) was determined on Monday morning and afternoon. The concentration of toluene diisocyanate (TDI) in air did not exceed 0.014 ppm on any occasion (multiple samples during each survey in all parts of the factory were taken). The exposed workers had reduction of ventilatory capacity at the afternoon measurement; the acute changes were not reversed overnight; cumulative changes exceeding those associated with aging occurred in these workers over 6, 12, and 18 months; symptomatic workers showed a greater response to TDI than asymptomatic ones; and a substantial positive correlation existed between the acute and cumulative changes in FEV1. |
| Databáze: | OpenAIRE |
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