Vitamin D in epilepsy: vitamin D levels in epilepsy patients, patients on antiepileptic drug polytherapy and drug-resistant epilepsy sufferers
| Autor: | L Rajanala, Sridhar Amalakanti, S Athina, Veeramma Uppala, Sundarachary Nagarjunakonda |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Vitamin Drug Resistant Epilepsy medicine.medical_specialty Medicine (miscellaneous) 030209 endocrinology & metabolism vitamin D deficiency 03 medical and health sciences chemistry.chemical_compound Epilepsy 0302 clinical medicine Pharmacotherapy Reference Values Internal medicine Prevalence Vitamin D and neurology Humans Medicine Vitamin D Nutrition and Dietetics business.industry Vitamin D Deficiency medicine.disease Obesity Endocrinology chemistry Sunlight Anticonvulsants Drug Therapy Combination Female business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Clinical Nutrition. 70:140-142 |
| ISSN: | 1476-5640 0954-3007 |
| DOI: | 10.1038/ejcn.2015.127 |
| Popis: | The objective of this study was to assess vitamin D levels in epileptic patients and to compare its serum levels in patients on antiepileptic monotherapy and polytherapy. We analyzed the serum 25-hydroxy (25-OH) vitamin D levels in 98 consecutive subjects (43 epileptic patients and 55 non-epileptics). Factors influencing its serum levels such as degree of sun exposure, physical activity and dietary intake were taken into consideration. Overall, 41% had deficient, 49% had insufficient and 9% had sufficient levels of serum vitamin D. Elderly individuals (>60 years) and people employed in offices and schools had lower blood vitamin D levels. Across both the sexes, epileptic patients and non-epileptics, epileptic patients on monotherapy and polytherapy and patients with drug-responsive and -resistant seizures, there were no significant differences in serum 25-OH vitamin D levels. Our study shows that people with epilepsy suffer with vitamin D deficiency along with their normal peers. |
| Databáze: | OpenAIRE |
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