Reliability of transcranial magnetic stimulation measurements of maximum activation of the knee extensors in young adult males
| Autor: | Christopher J. Tyler, Rachel Malcolm, Simon B. Cooper, Jonathan P. Folland, Caroline Sunderland, Ricci Hannah |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Intraclass correlation Coefficient of variation medicine.medical_treatment Biophysics Experimental and Cognitive Psychology 03 medical and health sciences Young Adult 0302 clinical medicine Isometric Contraction Medicine Humans Orthopedics and Sports Medicine Young adult Muscle Skeletal Reliability (statistics) Knee extensors business.industry Electromyography Reproducibility of Results 030229 sport sciences General Medicine Evoked Potentials Motor Transcranial Magnetic Stimulation Electric Stimulation Transcranial magnetic stimulation Sample size determination Nuclear medicine business Body mass index 030217 neurology & neurosurgery |
| ISSN: | 0167-9457 |
| Popis: | Purpose: Transcranial magnetic stimulation (TMS) provides an indication of changes occurring in the corticospinal pathway. This study aimed to determine the between-day (trials 1 week apart) and within-day (trials 1 h apart) reliability of TMS and peripheral nerve stimulation.\ud \ud Methods: 22 male participants (age 23 ± 4 years; height 1.80 ± 0.07 m; body mass 75.1 ± 11.7 kg; body mass index 23.1 ± 2.5 kg.m 2) completed 2 familiarisation sessions and 3 experimental trials (trial 2 and 3 split by 1 h). The interpolated twitch technique was used to determine TMS-assessed voluntary activations (VA-TMS) superimposed on submaximal and maximal leg extension performed on a custom-built dynamometer. Reliability was assessed using equivalence tests, systematic error, 95% limits of agreement, intraclass correlation coefficient (ICC) and coefficient of variation (CV).\ud \ud Results: VA-TMS was equivalent between-day (94.1 ± 4.4% versus 93.7 ± 4.9%, P < 0.01) and within-day (93.7 ± 4.9% versus 93.7 ± 4.8%, P < 0.01). Systematic error (95% limits of agreement) for VA-TMS was 0.5% (5.1%, 4.2%) for between-day and 0.0% 2 (5.3%, 5.4%) for within-day. ICC and CV values demonstrated high reliability between-day (ICC = 0.93, CV = 2.5%) and within-day (ICC = 0.92, CV = 2.9%).\ud \ud Conclusion: Results indicate that TMS can reliably estimate the output of the motor cortex to the knee extensors, both between-day and within-day. The findings have been used to estimate sample sizes for this technique for future research. |
| Databáze: | OpenAIRE |
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