Cancer Cachexia Affects Patients with Head and Neck Cancer in All Stages of Disease: A Prospective Cross-Sectional Study
| Autor: | Diana Cardenas, Obed Solís-Martínez, Karolina Álvarez-Altamirano, Vanessa Fuchs-Tarlovsky, Yanelly Trujillo-Cabrera |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty Cachexia Cross-sectional study Tooth loss Medicine (miscellaneous) Disease 03 medical and health sciences 0302 clinical medicine Oral hygiene Internal medicine Masticación Higiene oral medicine Dentition Humans Prospective Studies Stage (cooking) 030109 nutrition & dietetics Nutrition and Dietetics Squamous Cell Carcinoma of Head and Neck business.industry Caquexia Head and neck cancer Cancer cachexia medicine.disease Cross-Sectional Studies Pérdida de dientes Head and Neck Neoplasms 030220 oncology & carcinogenesis Dentición Mastication business |
| Zdroj: | Repositorio U. El Bosque Universidad El Bosque instacron:Universidad El Bosque |
| ISSN: | 1532-7914 0163-5581 |
| DOI: | 10.1080/01635581.2020.1869792 |
| Popis: | The aim of the study was to determine the prevalence of cancer cachexia according to the clinical stage and determine differences in body composition, usual energy intake, and proinflammatory profile between cachectic and non-cachectic patients newly diagnosed with head and neck squamous cell carcinoma (HNSCC). A cross-sectional study was conducted in adult patients diagnosed with HNSCC admitted to the oncology unit before starting cáncer treatment. Cancer cachexia was assessed according to Fearon criteria, and patients were divided into two groups: cachectic and non-cachectic patients. Body composition measured by bioelectrical impedance, energy intake, and biochemical and inflammatory markers were assessed. Comparative analyses were performed Student’s-T test, using one-way ANOVA, chi-square and Mann Whitney-U test. Of the 79 consecutive patients included in the analysis, 72% (n¼57; 61 ± 15 years) were classified as cachectic and 28% (n¼22;59 ± 10 years) as non-cachectic. According to clinical stage, the prevalence of cachexia was stage I¼8.8%, stage II ¼ 15.8%, stage III ¼ 33.3% and stage IV ¼ 42.1% (P¼0.564) and phase angle showed to be different between these groups (P |
| Databáze: | OpenAIRE |
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