Position statement on the diagnosis and management of non-alcoholic fatty liver disease
| Autor: | Naif Alturaify, Hind I Fallatah, Khalid Alswat, Abdullah Al-Osaimi, Hussien A Elsiesy, Adel N Qutub, Bandar Al-Judaibi, Waleed Al-Hamoudi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Diagnostic Imaging
medicine.medical_specialty medicine.medical_treatment Biopsy lcsh:Medicine Bariatric Surgery Disease 030204 cardiovascular system & hematology Liver transplantation Chenodeoxycholic Acid digestive system 03 medical and health sciences 0302 clinical medicine Chalcones Non-alcoholic Fatty Liver Disease medicine Prevalence Humans Insulin Mass Screening Vitamin E 030212 general & internal medicine Healthy Lifestyle Position Statement Intensive care medicine Mass screening medicine.diagnostic_test Pioglitazone business.industry lcsh:R Fatty liver NASH nutritional and metabolic diseases General Medicine medicine.disease digestive system diseases Liver Transplantation Fatty Liver Liver Liver biopsy Thiazolidinediones Clinical Practice Guidelines Metabolic syndrome Steatohepatitis Hydroxymethylglutaryl-CoA Reductase Inhibitors Propionates business Biomarkers |
| Zdroj: | Saudi Medical Journal Saudi Medical Journal, Vol 40, Iss 6, Pp 531-540 (2019) |
| ISSN: | 0379-5284 |
| Popis: | Non-alcoholic fatty liver disease (NAFLD) is a major national and international health burden. It is one of the most common liver diseases worldwide and the most common cause of abnormal liver enzymes in many developed countries. Non-alcoholic fatty liver disease is also known as an important cause of cryptogenic cirrhosis and second leading cause for liver transplantation. It is commonly associated with metabolic syndrome. Non-alcoholic steatohepatitis (NASH) is the progressive phenotype of NAFLD. In spite of promising performance of non-invasive tools, liver biopsy remains the gold standard test for NASH diagnosis. Over decades, many drugs have been investigated in phase 2 and 3; however, no approved therapy to date. Despite the alarming global rates of NAFLD, there are no local community-based studies on the prevalence of NAFLD or local practice guidelines on its management; this expert review aims to fill this gap. |
| Databáze: | OpenAIRE |
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