No clinical predictors of intraepithelial neoplasia in HIV-positive patients with external condilomata acuminata
| Autor: | Orietta Gómez, Claudia Ramis, Jonás Chnaiderman, Ester Santander, Paula Giacaman, Sandra Ampuero, María José Martínez, Ivo Sazunic, María Luisa Garmendia |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Gynecology
Sexually transmitted disease Human papilloma virus medicine.medical_specialty Intraepithelial neoplasia medicine.diagnostic_test Condylomata acuminata business.industry Public Health Environmental and Occupational Health Human immunodeficiency virus (HIV) virus diseases HIV Dermatology medicine.disease_cause Infectious Diseases human papilloma virus Internal medicine Biopsy Genotype medicine Histopathology Original Article business Genotyping |
| Zdroj: | Indian Journal of Sexually Transmitted Diseases |
| ISSN: | 2589-0565 |
| Popis: | To identify clinical parameters in association with human papilloma virus (HPV) genotypes and histopathology diagnosis in HIV-positive patients with external condylomata acuminata (ECA), 400 Chilean HIV-positive patients were included in the study. Forty-seven patients presented ECA. Clinical parameters and socio demographic data were recorded. Histopathology study and HPV linear array genotyping assay were performed. Intraepithelial neoplasia (IEN) grade 2 or 3 was found in 8.5% of patients, associated to HPV-16. Patients were mainly single, MSM, with history of sexually transmitted disease (STD), multiple sexual partners, receiving antiretroviral therapy and with recurrent lesions. All ECA were mainly perianal, grey or pink colored, exophytic with less than two years evolution. No clinical parameter could predict the development of high grade IEN in HIV patients with ECA. It seems necessary to perform biopsy and genotype all HIV positive patients with ECA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|