Saliva lithium monitoring in prepubertal children

Autor: Michael Cantwell, Sheridan Tucker, Elizabeth B. Weller, Mary A. Fristad, Ronald A. Weller
Rok vydání: 1987
Předmět:
Zdroj: Journal of the American Academy of Child and Adolescent Psychiatry. 26(2)
ISSN: 0890-8567
Popis: Serum and saliva lithium levels were simultaneously determined in 14 prepubertal children being treated with lithium carbonate. Saliva and serum lithium levels were strongly correlated. The concentration of lithium in saliva was almost two times (1.82) that in serum. There was more variability in saliva levels than in serum levels. It was possible to predict serum levels from saliva levels using regression analysis. If dose was added to saliva as a second predictor variable, accuracy of the prediction was increased.
Databáze: OpenAIRE