Effect of head posture on the healthy human carotid bifurcation hemodynamics

Autor: Papaharilaou, Yannis, Aristokleous, Nicolas, Seimenis, Ioannis, Khozeymeh, M. I., Georgiou, Georgios C., Brott, B. C., Eracleous, Eleni A., Anayiotos, Andreas S.
Přispěvatelé: Papaharilaou, Yannis [0000-0001-6441-2328], Aristokleous, Nicolas [0000-0002-0206-7773], Anayiotos, Andreas S. [0000-0003-4471-7604], Seimenis, Ioannis [0000-0003-3665-5271], Georgiou, Georgios C. [0000-0002-7451-224X]
Rok vydání: 2012
Předmět:
Male
Time Factors
Supine position
External carotid artery
Exposed to
Hemodynamics
Diseases
Computational fluid dynamics
Wall shear stress
Prone position
Blood vessels
Posture changes
Image-based
Head posture
Healthy subjects
nuclear magnetic resonance imaging
time
Oscillating walls
Cross sectional area
medicine.diagnostic_test
Arterial geometry
adult
Computational model
article
Healthy humans
health
Anatomy
Magnetic Resonance Imaging
Computer Science Applications
Wall region
Carotid Arteries
Health
Engineering and Technology
Oscillatory shear index
Internal carotid artery
Adult
Medical Engineering
Posture
Biomedical Engineering
Geometry
body posture
External carotid arteries
Geometry characterisation
Head and neck
male
vascularization
medicine.artery
Image-based CFD
medicine
Shear stress
Humans
human
business.industry
Residence time
Magnetic resonance imaging
head
Atherosclerosis
physiology
Head (vessel)
Morphology changes
business
Head
Carotid artery
Carotid bifurcation
Zdroj: Medical and Biological Engineering and Computing
Med.Biol.Eng.Comput.
ISSN: 1741-0444
0140-0118
DOI: 10.1007/s11517-012-0985-6
Popis: Head and neck postures may cause morphology changes to the geometry of the carotid bifurcation (CB) that alter the low and oscillating wall shear stress (WSS) regions previously reported as important in the development of atherosclerosis. Here the right and left CB were imaged by MRI in two healthy subjects in the neutral head posture with the subject in the supine position and in two other head postures with the subject in the prone position: (1) rightward rotation up to 80, and (2) leftward rotation up to 80. Image-based computational models were constructed to investigate the effect of posture on arterial geometry and local hemodynamics. The area exposure to unfavorable hemodynamics, based on thresholds set for oscillatory shear index (OSI), WSS and relative residence time, was used to quantify the hemodynamic impact on the wall. Torsion of the head was found to: (1) cause notable changes in the bifurcation and internal carotid artery angles and, in most cases, on cross-sectional area ratios for common, internal and external carotid artery, (2) change the spatial distribution of wall regions exposed to unfavorable hemodynamics, and (3) cause a marked change in the hemodynamic burden on the wall when the OSI was considered. These findings suggest that head posture may be associated with the genesis and development of atherosclerotic disease as well as complications in stenotic and stented vessels. © 2012 International Federation for Medical and Biological Engineering. 51 1-2 207 218 Cited By :7
Databáze: OpenAIRE
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