| Autor: |
Mehmet Ali Vardar, Ahmet Baris Guzel, Salih Taşkın, Mete Güngör, Nejat Özgül, Mehmet Coşkun Salman, Ümran Kucukgoz Gulec, Ghanim Khatib, Cağatay Taşkıran, Ilkkan Dünder, Fırat Ortaç, Kunter Yüce, Coşan Terek, Tayup Şimşek, Aydın Özsaran, Anıl Onan, Gonca Çoban Şerbetcioğlu, Samet Topuz, Fuat Demirkıran, Özgüç Takmaz, Mehmet Faruk Köse, Ahmet Göçmen, Gülşah Şeydaoğlu, Derya Gumurdulu, Ali Ayhan |
| Rok vydání: |
2021 |
| Předmět: |
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| Popis: |
Could the Long-Term Oncological Safety of Laparoscopic Surgery in Low Risk Endometrial Cancer be also valid for the High Intermediate and High-Risk Patients? A Multi-center Turkish Gynecologic Oncology Group Study Conducted with 2745 Endometrial Cancer Cases. (TRSGO-End-001)Aim: to compare the long-term oncological outcomes of laparotomy and laparoscopic surgeries in endometrial cancer under the light of 2016 ESMO-ESGO-ESTRO risk classification system with particular focus on the high intermediate and high-risk categories.Methods: Using multicentric database between January 2005 and January 2016, disease-free and overall survivals of 2745 endometrial cancer cases were compared according to the surgery route, laparotomy vs laparoscopy. The high intermediate and high-risk patients were defined with respect to the 2016 ESMO-ESGO-ESTRO risk classification system and they were analyzed with respect to difference in survival rates.Results: Of the 2745 patients 1743 (63.5%) were operated by laparotomy, and the remaining were operated with laparoscopy. The total numbers of high intermediate and high-risk endometrial cancer cases were 734 (45%) patients in the LT group and 307 (30.7%) patients in the LS group. Disease-free and overall survivals were not statistically different when compared between laparoscopy and laparotomy groups in terms of low, intermediate, high intermediate and high-risk endometrial cancer.Conclusions: Regardless of the endometrial cancer risk category, long-term oncological outcomes of laparoscopic approach were found to be comparable to those treated with laparotomy. Our results are encouraging to consider laparoscopic surgery for high intermediate and high-risk endometrial cancer cases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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