Comparison of Fluorodeoxyglucose Positron Emission Tomography and 111Indium–White Blood Cell Imaging in the Diagnosis of Periprosthetic Infection of the Hip
| Autor: | Stephen G. Pill, Charles A. Nelson, Jonathan P. Garino, Abass Alavi, Hongming Zhuang, Javad Parvizi, Peter Tang |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Reoperation medicine.medical_specialty Prosthesis-Related Infections Arthroplasty Replacement Hip medicine.medical_treatment Periprosthetic Scintigraphy Indium Sensitivity and Specificity Fluorodeoxyglucose positron emission tomography Sulfur colloid Positive predicative value White blood cell Leukocytes medicine Humans Orthopedics and Sports Medicine Prospective Studies Aged Pain Measurement Aged 80 and over medicine.diagnostic_test business.industry Middle Aged Arthroplasty Equipment Failure Analysis medicine.anatomical_structure Positron-Emission Tomography Technetium Tc 99m Sulfur Colloid Aseptic processing Radiology Radiopharmaceuticals business Biomarkers |
| Zdroj: | The Journal of Arthroplasty. 21:91-97 |
| ISSN: | 0883-5403 |
| DOI: | 10.1016/j.arth.2006.05.021 |
| Popis: | We aimed to compare the accuracy of fluorodeoxyglucose positron emission tomography (FDG-PET) with technetium-99m sulfur colloid 111indium-labeled white blood cell scintigraphy (TcSC-Ind BM/WBC) in diagnosis of periprosthetic infection. Eighty-nine patients with 92 painful hip prostheses were recruited prospectively and given the option of undergoing either combined FDG-PET and TcSC-Ind BM/WBC or FDG-PET only. FDG-PET correctly diagnosed 20 of the 21 infected cases (sensitivity, 95.2%) and ruled out infection in 66 of the 71 aseptic hips (specificity, 93%) corresponding to a positive predictive value of 80% (20/25) and a negative predictive value of 98.5% (66/67). TcSC-Ind BM/WBC correctly identified 5 of the 10 infected cases (sensitivity, 50%) and 39 of 41 aseptic cases (specificity, 95.1%) corresponding to a positive and negative predictive values of 41.7% (5/12 cases) and 88.6% (39/44 cases), respectively. Based on these preliminary results, FDG-PET appears to be a promising diagnostic tool for distinguishing septic from aseptic painful hip prostheses. |
| Databáze: | OpenAIRE |
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