Distribution of omega-3 fatty acids in tissues of rabbits fed a flaxseed-supplemented diet
| Autor: | Andrea L. Edel, Richelle S. McCullough, Grant N. Pierce, Anton Lukas, Bradley P. Ander, Penelope Rampersad, Delfin Rodriguez-Leyva, James S. C. Gilchrist |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Chromatography Gas 030309 nutrition & dietetics Linolenic acid Endocrinology Diabetes and Metabolism 03 medical and health sciences chemistry.chemical_compound Random Allocation Endocrinology Internal medicine Flax medicine Distribution (pharmacology) Animals Tissue Distribution Tissue distribution 030304 developmental biology 2. Zero hunger chemistry.chemical_classification Random allocation 0303 health sciences alpha-Linolenic Acid Eicosapentaenoic acid 3. Good health chemistry Docosahexaenoic acid Dietary Supplements Arachidonic acid Rabbits Polyunsaturated fatty acid |
| Zdroj: | Metabolism: clinical and experimental. 59(5) |
| ISSN: | 1532-8600 |
| Popis: | Diets rich in omega-3 polyunsaturated fatty acids are associated with decreased incidences of cardiovascular disease. The extent of incorporation and distribution of these beneficial fats into body tissues is uncertain. Rabbits were fed regular rabbit chow or a diet containing 10% ground flaxseed that is highly enriched with the omega-3 polyunsaturated fatty acid alpha-linolenic acid (ALA). The high-flaxseed diet resulted in an incorporation of ALA in all tissues, but mostly in the heart and liver with little in the brain. Docosahexaenoic and eicosapentaenoic acid levels were also selectively increased in some tissues, and the effects were not as large as ALA. Arachidonic acid and the ratio of omega-6/omega-3 fatty acids were decreased in all tissues obtained from the flax-supplemented group. Consumption of dietary flaxseed appears to be an effective means to increase ALA content in body tissues, but the degree will depend upon the tissues examined. |
| Databáze: | OpenAIRE |
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