The Genus Patrinia: A Review of Traditional Uses, Phytochemical and Pharmacological Studies
Autor: | Mao-xing Li, Qiang Zhang, Linhong Huang, Ni Wu, Xirui He, Ning Ning, Ling Jin, Zefeng Zhao, Fei Luan, Yu Chang |
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Rok vydání: | 2017 |
Předmět: |
Phytochemistry
medicine.drug_class Anti-Inflammatory Agents Biology Pharmacology Antiviral Agents 01 natural sciences Lignans Anti-inflammatory Dysentery Erysipelas 03 medical and health sciences Patrinia 0302 clinical medicine Triterpenoid Genus Conjunctival congestion medicine Animals Humans Iridoids Medicinal plants Flavonoids Plant Extracts General Medicine Saponins biology.organism_classification Antineoplastic Agents Phytogenic Abscess Triterpenes Anti-Bacterial Agents 0104 chemical sciences 010404 medicinal & biomolecular chemistry Complementary and alternative medicine Phytochemical 030220 oncology & carcinogenesis Phytotherapy |
Zdroj: | The American Journal of Chinese Medicine. 45:637-666 |
ISSN: | 1793-6853 0192-415X |
Popis: | The aim of the present review is to comprehensively outline the botanical description, traditional uses, phytochemistry, pharmacology and toxicology of Patrinia, and to discuss possible trends for the further study of medicinal plants from the genus Patrinia. The genus Patrinia plays an important role in Asian medicine for the treatment of erysipelas, conjunctival congestion with swelling and pain, peri-appendicular abscesses, lung carbuncle, dysentery, leucorrhea, and postpartum disease. More than 210 chemical constituents have been isolated and identified from Patrinia plants, especially P. scabiosaefolia Fisch., P. scabra Bunge, P. villosa Juss., P. heterophylla Bunge and P. rupestris(Pall.) Juss[Formula: see text] Of these compounds, triterpenoids and saponins, iridoids, flavonoids, and lignans are the major or active constituents. Both in vitro and in vivo studies have indicated that some monomer compounds and crude extracts from the genus Patrinia possess wide pharmacological activities, including antitumor, anti-inflammatory, antibacterial, and antiviral effects. In addition, they have been shown to have valuable and positive effects on the immune and nervous system in experimental animals. There are also some reports on the clinical uses and toxicity of these species. However, few reports have been published concerning the material identification or quality control of Patrinia species, and the clinical uses and toxic effects of these plants are relatively sparse. More attention must be given to these issues. |
Databáze: | OpenAIRE |
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