Bevacizumab for Occult Subfoveal Neovascularization in Age-Related Macular Degeneration
| Autor: | Libondi T, B Harder, Ulrich H. M. Spandau, Jb Jonas, Gangolf Sauder, Bernd A. Kamppeter |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Vascular Endothelial Growth Factor A
Fovea Centralis Intraocular pressure medicine.medical_specialty Visual acuity genetic structures Bevacizumab Angiogenesis Inhibitors Retinal Neovascularization Antibodies Monoclonal Humanized Injections Neovascularization Macular Degeneration 03 medical and health sciences 0302 clinical medicine Optical coherence tomography Edema Ophthalmology Humans Medicine Aged medicine.diagnostic_test business.industry Antibodies Monoclonal Exudates and Transudates General Medicine Macular degeneration medicine.disease Occult eye diseases Vitreous Body 030221 ophthalmology & optometry Optometry Female sense organs medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery Follow-Up Studies medicine.drug |
| Zdroj: | European Journal of Ophthalmology. 16:774-775 |
| ISSN: | 1724-6016 1120-6721 |
| Popis: | Purpose To report on the treatment of exudative age-related macular degeneration by intravitreal bevacizumab (Avastin). Methods A 78-year-old patient experienced a progressive loss of visual acuity in her right eye due to an occult subfoveal neovascular membrane in age-related macular degeneration. She received an intravitreal injection of 1.5 mg bevacizumab. Results Within 4 weeks after the injection, visual acuity improved from 0.40 to 0.60 with complete resolution of subretinal and intraretinal leakage and edema as shown on optical coherence tomography. Pre-existing metamorphopsias disappeared. Intraocular pressure remained in the normal range. During the follow-up, there were no sings of intraocular inflammation or any other intraocular pathology induced by the intravitreal injection. Conclusions Intravitreal bevacizumab may potentially be helpful in the treatment of exudative age-related macular degeneration and may deserve further evaluation. |
| Databáze: | OpenAIRE |
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