Main properties of nanocrystalline hydroxyapatite as a bone graft material in treatment of periodontal defects. A review of literature
| Autor: | Aysan Shahnaz, Sepehr Torabi, Mohammad Pourali, Mojtaba Bayani |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Biocompatibility
lcsh:Biotechnology bone graft Dentistry 02 engineering and technology Bone healing Biological apatite 03 medical and health sciences 0302 clinical medicine Bone graft materials lcsh:TP248.13-248.65 periodontal regeneration medicine Dental alveolus Periodontitis business.industry Regeneration (biology) Osteoblast 030206 dentistry 021001 nanoscience & nanotechnology medicine.disease Nanocrystalline hydroxyapatite medicine.anatomical_structure periodontal defects 0210 nano-technology business Biotechnology |
| Zdroj: | Biotechnology & Biotechnological Equipment, Vol 31, Iss 2, Pp 215-220 (2017) |
| ISSN: | 1314-3530 1310-2818 |
| Popis: | This study aims to provide a literature review on nanocrystalline hydroxyapatite (n-HA). n-HA constitutes the principle inorganic part of hard tissues. Therefore, preparation of commercial synthetic analogues, the so-called ‘biomimetic’, has gained a lot of attention since it can precisely mimic the physicochemical features of biological apatite compounds. Due to its improved osseointegrative properties, n-HA may represent a promising class of bone graft materials. n-HA binds to the bone and by stimulation of osteoblast activity and enhancing local growth factors it improves bone healing. Periodontitis is an inflammatory condition in response to microbial plaque that leads to periodontal tissue destruction and osseous defects in alveolar bone. A review of the extant literature reveals that n-HA has certain advantages in periodontal tissue regeneration including minimal patient morbidity, better biocompatibility, and lack of toxicity. |
| Databáze: | OpenAIRE |
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