Evaluation of inflammatory processes by FTIR spectroscopy
| Autor: | Janete Dias Almeida, Ana Lia Anbinder, Laís Morandini Rodrigues, Franck Bonnier, Herculano da Silva Martinho, Luis Felipe das Chagas e Silva de Carvalho |
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| Přispěvatelé: | São Paulo State University ( UNESP ), Universidade de Taubaté ( UNITAU ), Nanomédicaments et Nanosondes, EA 6295 ( NMNS ), Université de Tours, Universidade Federal do ABC ( UFABC ), Universidade Estadual Paulista (Unesp), Universidade de Taubaté, Universidade Braz Cubas, Université François-Rabelais de Tours, Universidade Federal do ABC (UFABC), Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University (UNESP), Universidade de Taubaté (UNITAU), Nanomédicaments et Nanosondes, EA 6295 (NMNS), Université de Tours (UT) |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
diagnosis Biopsy Biomedical Engineering 01 natural sciences 03 medical and health sciences Nuclear magnetic resonance [CHIM.ANAL]Chemical Sciences/Analytical chemistry Spectroscopy Fourier Transform Infrared Biochemical composition Humans Fourier transform infrared spectroscopy Spectroscopy chemistry.chemical_classification Inflammation Hyperplasia inflammatory tissue 010401 analytical chemistry Mouth Mucosa General Medicine 0104 chemical sciences 3. Good health Amino acid Fibrous hyperplasia FTIR spectroscopy 030104 developmental biology chemistry FTIR [ CHIM.ANAL ] Chemical Sciences/Analytical chemistry inflammatory processes |
| Zdroj: | Journal of Medical Engineering and Technology Journal of Medical Engineering and Technology, Informa Healthcare, 2018, 42 (3), pp.228-235. 〈10.1080/03091902.2018.1470691〉 Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Journal of Medical Engineering and Technology, Informa Healthcare, 2018, 42 (3), pp.228-235. ⟨10.1080/03091902.2018.1470691⟩ |
| ISSN: | 1464-522X 0309-1902 |
| DOI: | 10.1080/03091902.2018.1470691〉 |
| Popis: | Made available in DSpace on 2018-12-11T17:20:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-03 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Fourier transform infrared (FTIR) spectroscopy is a powerful diagnosis technique and has been used to identify patterns of molecular changes based on vibration modes. The objective of this study was to evaluate inflammatory fibrous hyperplasia (IFH) lesions and oral normal mucosa (NM) initially with histopathological exam and then using micro-FTIR spectroscopy to analyse the samples. Eleven IFH and 11 NM samples were analysed at five different points to cover the largest area possible by the micro-FTIR technique. Bands were observed between 970 and 1743 cm−1 which corresponded to different structural components like collagen, lipids, fatty acids, proteins and amino acids. Spectral bands were more intense mostly for IFH lesions, including collagen bands, which are an important component of inflammatory fibrous hyperplasia. This study demonstrated that differentiation in the inflammatory tissue was observed in FTIR spectral differences, in terms of biochemical composition. Department of Bioscience and Oral Diagnosis Institute of Science and Technology of São José dos Campos Univ Estadual Paulista-UNESP Departamento de Odontologia Universidade de Taubaté Graduação em Odontologia Universidade Braz Cubas Faculty of Pharmacy Université François-Rabelais de Tours Centro de Ciências Naturais e Humanas Universidade Federal do ABC Department of Bioscience and Oral Diagnosis Institute of Science and Technology of São José dos Campos Univ Estadual Paulista-UNESP |
| Databáze: | OpenAIRE |
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