A comparison of panoramic radiographic findings in patients with familial adenomatous polyposis and the general population: a multicenter study
| Autor: | Thomas M. Attard, Lynn Roosa Friesen, Seth Septer, Camila Pacheco-Pereira, Eliete Neves Silva Guerra, Ana Carolina Acevedo, Hassem Geha, Fabiana Tolentino Almeida |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
congenital hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Panoramic radiograph Radiography Population Disease Pathology and Forensic Medicine Familial adenomatous polyposis Radiography Panoramic medicine Prevalence Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) In patient education Child neoplasms Dental anomalies education.field_of_study business.industry medicine.disease digestive system diseases Cross-Sectional Studies Multicenter study Adenomatous Polyposis Coli Surgery Oral Surgery business |
| Zdroj: | Oral surgery, oral medicine, oral pathology and oral radiology. 133(3) |
| ISSN: | 2212-4411 |
| Popis: | Familial adenomatous polyposis (FAP) is a hereditable disorder characterized by early and unremitting development of intestinal polyps and extraintestinal manifestations requiring multidisciplinary surveillance. Herein we describe a multicenter cross-sectional analysis of the dento-osseous radiographic findings of patients with FAP from North and South America.Groups I and II included individuals with FAP diagnosed by standard clinical criteria. Patients were paired with age- and sex-matched participants without FAP. Panoramic radiograph of both cohorts, including children and adults, were analyzed.Of 114 panoramic radiographs, 38 were from patients with FAP, composed of group I (n = 22) and group II (n = 16), and 76 were from matched control participants. Evaluators had excellent agreement on key findings (intraclass correlation coefficient = 0.89). The prevalence of osseous anomalies was higher in adults (75%) than in children (65.4%). Dental anomalies were also higher in children with FAP with a prevalence of 15.4%.We describe important and significant differences in the prevalence of dento-osseous anomalies in children compared with adult patients with FAP. These findings warrant careful consideration and may influence multidisciplinary management of the condition. Conversely, the presence of these abnormalities in pediatric dental patients even if not diagnosed with FAP should be borne in mind as possibly indicating de novo or unrecognized disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect